The Growing-Block: just one thing after another?

One thing leads to another.

In 1956, the JCI published an article by Vincent Dole on a method for titrating plasma fatty acids that uncovered the importance of fatty acids as a substrate for glucose metabolism. When asked to prepare a historical perspective on this very popular paper, I paid Dole a visit and we reminisced. His answer to my question of how he came to do this work on plasma fatty acids was: "Well, one thing...

Aging: One Thing Leads to Another

Mitochondria deteriorate during the aging process, but the underlying mechanisms for the decline of this critical organelle are unknown. A new study indicates that in yeast an age-dependent reduction in vacuolar acidification leads to mitochondrial dysfunction through a surprising mechanism: loss of vacuolar neutral amino acid transport.

Just Another Manic Monday: Peaking Sexual Concerns After the Weekend

The so-called‘‘weekendeffect’’is a well-knownphenomenon in thestockmarket (Keim&Stambaugh,1984).This relates tosignificantly lower stock returns on Monday in comparison with other days of the week. It is suggested that this effect could be a result of traders’ fading optimism between Friday and Monday. Interestingly, similar‘‘weekend effects’’can also be found in health-related matters. The num...

Just Another Test?

"Just another headache".